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br Experimental Procedures br Acknowledgments br Introductio
2020-06-23
Experimental Procedures Acknowledgments Introduction Incessant consumption of fossil fuels brings on global energy crisis and serious environmental concerns. Hence, the researchers have paid considerable attention to alternative renewable bioenergy. Microalgae has been considered as potenti
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br Conclusion br Funding source br Ethical approval br
2020-06-23
Conclusion Funding source Ethical approval Conflict of interest statement Introduction Traditionally, schizophrenia (SZ) was thought to be associated with neuronal dysfunction; however, the current hypothesis that myelin and, specifically, oligodendrocytes are also involved in the dev
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c-kit AMPK is a master regulator
2020-06-23
AMPK is a master regulator of metabolic homeostasis, its broad spectrum of metabolic activities makes it an attractive target for treatment of metabolic and related disorders including Diabetes and Obesity (Madhavi et al., 2018). It controls lipid metabolism through its target genes PPAR-γ, C/EBP-α
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The small intestine is the only organ responsible for the
2020-06-23
The small intestine is the only organ responsible for the Topotecan HCl mg of dietary and biliary cholesterol, leaving the unabsorbed cholesterol to be excreted in feces and together contributing to the body cholesterol homeostasis [13], [21], [33], [34]. Following intraluminal hydrolysis, free cho
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br DNA PK After sensing and
2020-06-23
DNA-PK After sensing and binding to the DSB, Ku quickly recruits DNA-PKcs to the site of the DNA break. Similar to Ku70/80, recruitment of DNA-PKcs to DSBs occurs within seconds of their creation [12]. The interaction between Ku70/80 and DNA-PKcs requires the presence of dsDNA and the complex for
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We experienced difficulties in observing maturation of hESC
2020-06-23
We experienced difficulties in observing maturation of hESC retinas in rd1 mice even with immunosuppression, but with NOG-rd1-2J mice the transplanted hESC retinas consistently developed mature ONL with rod and cone opsins. Furthermore, graft photoreceptors show signs of developing IS/OS structures
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This approach is similar to that suggested
2020-06-23
This approach is similar to that suggested by the previous edition of the GL [6]. Not surprisingly, the questions to be answered are the same (i.e., was the event TLOC? In cases of TLOC, is this FH1 of syncopal or non-syncopal origin? In cases of suspected syncope, is there a clear aetiological dia
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br Conclusions ERK and its phosphorylation plays an essentia
2020-06-23
Conclusions ERK 1/2 and its phosphorylation plays an essential role in the hippocampus and can be triggered by both ROS accumulation and excessive Ca2+. DBP exposure can also affect the production of ROS and Ca2+ in the hippocampus. The question therefore arises as to whether the cell injury or a
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The purposes of this study are to
2020-06-23
The purposes of this study are to investigate the molecular function of DDR2, especially in cellular proliferation in prechondrocytes, and to examine the relationship between the proliferation and differentiation of prechondrocytes through both in vitro and in vivo analysis. Materials and methods
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As a transcription factor HOXA regulates multiple target gen
2020-06-22
As a transcription factor, HOXA9 regulates multiple target genes related to cell growth, including BRCA1 [34], BCL-2 [35], c-MYB [36], IGF1 [37], PIM1 [38] and so on. In addition, HOXA9 is a member of both activating and repressive transcriptional regulatory complexes, along with cofactor and collab
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Preliminary studies suggest that dimerization of the AT
2020-06-22
Preliminary studies suggest that dimerization of the AT1 receptor occurred during the biosynthesis in the endoplasmic reticulum before surface expression [27,40], which may explain the presenece of these Penciclovir mg before the addition of any ligand. Our results showed that the presence of Ang
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br Methods br Results br
2020-06-22
Methods Results Discussion The lowest intra-CeA dose of R278995/CRA0450 that prevented the elevations in DAPI hydrochloride reward thresholds associated with nicotine withdrawal was 0.05μg/side (0.1μg total bilateral dose). The total bilateral dose in the present study is 100 times lower th
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In the present study we have examined an
2020-06-22
In the present study, we have examined, an alternative approach for introduction of Hyp into bacterial, non-animal collagens. Previously, Gruskin and colleagues [27] had shown that Hyp could be introduced into recombinant mammalian collagen sequences in E. coli through a mechanism of co-translationa
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br Transparency document br Results and Discussion br
2020-06-22
Transparency document Results and Discussion Experimental Procedures Acknowledgments The casein kinase 1 (CK1) family consists of at least seven different gene products, often referred to as isoforms (α, β, γ1, γ2, γ3, δ, ε, with splice forms described for CK1α, γ, and ε (reviewed in )
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br Experimental Procedures br Author Contributions br Acknow
2020-06-22
Experimental Procedures Author Contributions Acknowledgments Introduction The intestinal mucosal barrier surface is constantly exposed to food antigens, beneficial microbes, pathogens, and a multitude of other environmental stimuli (Turner, 2009). Innate lymphoid VX-702 (ILCs) are known
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