HCV has evolved mechanisms to evade humoral

2019-08-24

HCV has evolved mechanisms to evade humoral immune responses including high functional flexibility and variability of immunogenic portions of its envelope proteins.

Introduction Concern has been raised over

2019-08-24

Introduction Concern has been raised over free estrogens (estrone [E1], 17ß-estradiol [E2] and 17α-ethynylestradiol [EE2] particularly) in the past decade due to their endocrine disrupting effects on environmental biota [1], [2].

The enzymatic activity of recombinant

2019-08-23

The enzymatic activity of recombinant sponge P4H was assayed in vitro both at 37°C, the standard enzymatic kinetics temperature, and at 15°C, the typical sea temperature of C. reniformis marine environment (Fig. 2C).

In the belief that DNA based

2019-08-22

In the belief that DNA-based nanosensors and DNA microarrays should be easier to operate, faster, more accurate and more economically viable than PCR-based techniques, an electrochemical DNA biosensor was designed for detection of G. boninense[9], [10].

The repair pathway of DNA DSBs through HR and

2019-08-21

The repair pathway of DNA-DSBs through HR and the role of BRCA1 in repair kinetics by HR is also an important factor to unravel the radiation sensitization of novel small molecule inhibitors.

Application of the CPH model relies

2019-08-20

Application of the CPH model relies on the assumption that the hazard ratio of two observations is constant over time [2].

Likewise the conserved cysteine in the E protein is the

2019-08-19

Likewise, the conserved cysteine in the E2 protein is the only residue shown to be essential for the transfer of Ub/Ubl from E2 to the HECT ligases (Dye and Schulman, 2007, Wu et al., 2003).

Consistent with our previous study Gao et al

2019-08-17

Consistent with our previous study (Gao et al., 2018b; Wu et al., 2018), we found that TCB-2 disrupted both pup preference and home-cage maternal behavior.

This project was funded by the Deutsche Forschungsgemeinscha

2019-08-16

This project was funded by the Deutsche Forschungsgemeinschaft within FOR 2251 (project grants EB 285/2-1 and WI 3272/3-1) and in part by additional contributions from the Bundesministerium für Bildung und Forschung (D.I.S award Nos. BIOSCAT [05K12YE1]) and the Horizon 2020 programme of the European Union, iNEXT [653706; D.I.S].

The quaternary structure of many of the family B members

2019-08-15

The quaternary structure of many of the family B members (i.e., secretin, glucagon, glucagon-like peptide and Celastrol receptors) have been actively studied and it has been demonstrated that they can form homodimers/oligomers (Gao et al., 2009; Ng & Chow, 2015; Ng, Lee, & Chow, 2013).

The importance of mitochondria as

2019-08-14

The importance of mitochondria as site of aerobic oxidation of metabolic fuels, such as FA, has been recognized for a long time.

Introduction O Methylguanine DNA methyltransferase MGMT

2019-08-13

Introduction O6-Methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that specifically transfers alkyl adducts from the O6 position of guanine to the cysteine residue (Cys145) in its active site.

Hello world!

2018-07-29